SP8a: EbM - Meta Analysis

Evidence-based medicine is defined as the conscientious, explicit and judicious use of current best evidence in making clinical decisions about the care of patients, thereby integrating individual clinical care with the best available clinical evidence from high-quality clinical trials and systematic reviews. The EbM care in lymphoma patients is of a high quality, but many important results are not well-elaborated and easily accessible.

Aim of the project was to systematically develop a meta-regression technique to estimate the slope of the effective dose/cure relationship as well as an average latency time and relative substance weights form randomised trials comparing chemotherapies. The method was to be applied to all Hodgkin’s lymphoma and Non-Hodgkin’s lymphoma trials, especially from randomized controlled trials.

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