Designation

Cell type

Antigen

CD1a

Cortical thymocytes, subpopulation of B cells, dendritic cells

MCH-like protein, can associate with b₂-microglobulin

CD2

T cells, most NK cells

Erythrocyte-rosette receptor, ligand for leukocyte function antigen 3

CD3

Surface expression on mature T cells, cytoplasmic expression in immature T cells

Associated with the T cell receptor, mediates signal transduction

CD4

Helper/inducer T lymphocytes, immature myeloid cells

Receptor for MHC II molecules and HIV

CD5

Thymocytes, mature T cells, subpopulation of B cells

Linked to T cell proliferation

CD7

T cells, NK cells, subpopulation of immature myeloid cells

40 kDa protein

CD8

Cytoxic/suppressor T cells, subpopulation of NK cells

Receptor for MHC I molecules

CD10

c-ALL, lymphatic precursor cells, neutrophils, subset of mature B cells

Common acute leukemia antigen (CALLA), neutral endopeptidase (enkephalinase)

CD11b

Monocytes, macrophages, neutrophils, NK cells

Adhesion molecule, C3bi receptor

CD11c

Monocytes, neutrophils, NK cells, subpopulation of B cells

Adhesion molecule, gp 150/95

CD13

Myeloid cells

Aminopeptidase N

CD14

Monocytes, weak expression on neutrophils

LPS receptor

CD15

Neutrophils, weak expression on monocytes

X-hapten, 3-fucosyl-N-acetyl-lactosamine

CD16

NK cells, neutrophils, subpopulation of monocytes

Low-affinity Fc-receptor for IgG

CD19

Precursor B cells, B cells

Bridge for surface immunglobulin signal

CD20

Subpopulation of precursor B cells, B cells

ion channel, protein kinase C substrate

CD22

Surface expression on B cells, cytoplasmic expression in precursor B cells

Related to neural cell adhesion molecule, bridge for surface immunglobulin signal

CD23

Subpopulation of B cells

Low-affinity Fc-receptor for IgE

CD24

B lymphocytes, activated T lymphocytes, neutrophils

35-45 kDa glycosylphosphatidylinositol-linked glycoprotein

CD25

Activated T and B lymphocytes

Interleukin-2-receptor a-chain

CD33

Monocytes, myeloid precursor cells, weak expression on neutrophils

67 Kda glycoprotein

CD34

Myeloid and lymphoid precursor cells

105-120 kDa glycoprotein

CD38

Activated lymphocytes, subpopulation of B cells, plasma cells

45 kDA glycoprotein

CD41a

Platelets, megakaryocytes

Glycoprotein IIb/IIa, fibrinogen receptor

CD42b

Platelets, megakaryocytes

Glycoprotein Ib, part of the Willebrand factor receptor

CD45

All leukocytes

T200 antigen, protein-tyrosin-phosphatase

CD61

Platelets, megakaryocytes

Glycoprotein IIIa, vitronectin receptor b-chain

CD64

Monocytes, macrophages

High-affinity receptor for IgG

CDw65

Neutrophils, weak expression on monocytes

Ceramide dodecasaccharide 40

CD71

Erythroid cells, activated T and B lymphocytes, macrophages

Transferrin receptor

CD79a

B lymphocytes, including immature B cells

Ig- a/mb-1, part of the B cell antigen receptor

CD103

Intraepithelial lymphocytes

HML-1

CD117

Myeloid precursor cells

C-kit, stem cell factor receptor

FMC7

Differentiated B lymphocytes

105 kDA glycoprotein

Glycophorin A

Erythrocytes, erythroblasts and erythroid precursor cells

Sialinic acid-rich polypeptide

HLA-DR

B lymphocytes, activated T lymphocytes, monocytes, precursor cells

Part of the MHC II complex

MPO

Lysosomal expression in neutrophils and monocytes, including immature myeloid cells

Myeloperoxidase

TdT

Nuclear expression in lymphoid precursor cells

Terminal deoxynucleotidyl transferase

TcR a/ b

Majority of T lymphocytes

a/ b chains of T cell receptor

TcR g/ d

Subset of T lymphocytes

g/ d chains of T cell receptor

Kappa

Surface expression on B lymphocytes

Immunoglobulin-light chain type kappa

Lambda

Surface expression on B lymphocytes

Immunoglobulin-light chain type lambda

Ig -chain

B lymphocytes

Immunoglobulin M-heavy chain